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Tadalafil 40 MG

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Tadalafil 40 MG


Tadalafil 40mg - Cialis 40mg

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Starting from $0.75

Generic Tadalafil 40mg is an orally administered drug indicated for the management of erectile dysfunction. It relaxes the blood vessels in the penis, thus allowing the flow of blood into the penis during sexual stimulation; which results in improved erectile dysfunction. It is a highly potent pill which gives a long lasting effect up to 36 hours. Generic Tadalafil 40mg is a main active component of Tadalafil 40mg. Tadalafil 40mg is an effective phosphodiesterase-5 inhibitor. By inhibiting the production of phosphodiesterase type-5, the erections in men can be maintained for a longer time and with a greater blood supply.

Quantity Strength Price Unit Price
40 Tablets Tadalafil Generic 40mg $40.00 $1.00
60 Tablets Tadalafil Generic 40mg $54.00 $0.90
100 Tablets Tadalafil Generic 40mg $75.00 $0.75

Mechanism Of Action Of Tadalafil 40mg

Tadalafil 40mg is a selective inhibitor of phosphodiesterase-5, which increases cyclic GMP thus, enhancing the erectile function. Penile erection is caused by increased penile blood flow resulting from the relaxation of penis arteries and smooth muscles. This action is mediated by the discharge of nitric oxide from endothelial cells and nerve terminals, which stimulates the synthesis of c-GMP in the smooth muscle cells. Cyclic GMP causes relaxation of smooth muscle resulting in increased blood flow into the smooth muscles of penis. The inhibition of phosphodiesterase-5 therefore, enhances erectile function by increasing the amount of c-GMP.

Therapeutic Uses Of Tadalafil 40mg

The medicine is approved to treat symptoms of erectile dysfunction and benign prostatic hyperplasia.

Drug Interactions

This medicine should not be taken with these particular classes of drugs:

  • Nitrates such as Isoniazid, Isosorbide mononitrate and Isosorbide dinitrate, amyl nitrite as these can cause a sudden decrease in blood pressure.
  • Antifungal drugs such as fluconazole, ketoconazole, Itraconazole, Voriconazole.
  • Antidepressants such as Nefazodone
  • Anti-hypertensive drugs (including calcium channel blockers) such as Amlodipine
  • 5- Alpha reductase inhibitors such as Finasteride.
  • CYP1A2 substrates (e.g. Theophylline)
  • Alcohol, warfarin
  • Antiviral drugs such as Efavirenz, Indinavir, Ritonavir, Saquinavir, Fosamprenavir, Phenobarbital.
  • Antiepileptic drugs such as Carbamazepine, Phenytoin, Phenobarbital.

Contraindications

  • Use of Tadalafil 40mg to patients who are taking any form of organic nitrate is contraindicated as Tadalafil 40mg increases the hypotensive effect of nitrates.
  • Cardiac patient should not use this drug.
  • The medicine is contraindicated in patients with a known serious hypersensitivity to Tadalafil 40mg. These hypersensitivity reactions include Stevens-Johnson syndrome or dermatitis.

Storage Of Tadalafil 40mg

  • The medicine should be kept out of reach of children.
  • It should be kept away from the contact of sunlight and moisture.
  • The medicine should be stored at room temperatures between 15 and 300 C.

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Dosage Of Tadalafil 40mg

Generic Tadalafil 40mg is available as a film-coated almond shaped tablet for oral administration. The recommended starting dose of Generic Tadalafil 40mg is taken at least 15 minutes prior to sexual activity. The medicine should be consumed with a full glass of water. It should be taken in a duration ranging from 30 to 60 minutes before engaging in sexual activity. One tablet of Tadalafil 40mg is sufficient for 24 hours and don't get any other dose of Tadalafil 40mg within 24 hours. The tablet may be taken with or without food and the entire tablet should be taken without splitting into pieces.


Missed dose

Missed dose can be taken as soon as you remember. The missed dose may be skipped if it is almost time for your next scheduled dose. Extra medicine should not be taken to constitute the missed dose.


Overdose

In occurrence of any overdose symptoms of Tadalafil 40mg then immediately consult your physician. Some overdose symptoms of Tadalafil 40mg are chest pain, vertigo, shortness of breath.

Side Effects Of Tadalafil 40mg

The most common side effects accompanied with the use of this medicine are headache, back pain, indigestion, nausea, muscle ache, flushing, cough, blurred vision, nasal congestion. These side effects persist only for a few hours.

The uncommon side effects include changes in colour vision that is having difficulty in differentiating between the colours like blue and green; abrupt decline or loss of vision in one or both eyes; sudden decrease or loss in hearing.

Safety Precautions

  • This medicine should not be used with grapefruit juice as it delays the activity of Tadalafil 40mg.
  • Tobacco or alcoholic beverages should not be consumed with this drug.
  • In case of any birth defects of penis like curved penis or complaints of coronary artery disease, arrhythmia, diabetes, hypo- or hypertension, angina, bleeding, stomach ulcers; the physician should be informed.