Mifepristone blocks a natural chemical in the body (hormone, progesterone) that is required for your pregnancy to continue.
“A drug - drug interaction occurs when one drug (medical treatment 1) affects the activity of another drug (treatment 2) when both of them are administered collectively.”
Some medicines that may interact with this drug include:
- Long-term corticosteroids (for example, prednisone, dexamethasone or methylprednisolone)
- Azole antifungal drugs such as ketoconazole or itraconazole
- Macrolide antibiotics comprising rifabutin, erythromycin, rifamycin or dexamethasone
- Herbal drugs like St. John's Wort
- Anti-seizure drugs such as phenytoin, carbamazepine or phenobarbital
- Antiplatelet medicines such as clopidogrel
- Non-steroidal anti-inflammatory drugs such as Ibuprofen, Aspirin
Who Should Not Take Mifeprex?
DO NOT take this drug if:
- It had been more than 7 weeks (49 days) since your last menstrual period began.
- You have been using an intrauterine device. It must be taken out before you take Mifeprex.
- You have a pregnancy outside the uterus (ectopic pregnancy).
- You have complications with your adrenal glands (chronic adrenal failure).
- You take a drug to thin your blood or an anticoagulant like Coumadin or Warfarin.
- You are suffering from a bleeding disorder.
- You take certain steroid drugs.
- You are hypersensitive to Mifepristone, Misoprostol, or other prostaglandins.
- This medicine should be stored in a cool and dry place at the room temperature 30°C.
- Keep it out of reach of children and pets.
- Protect it from light and moisture.
MIFEPREX: A HIGHLY RELIABLE AND CONVENIENT PRODUCT FOR YOU!!!
Dosing Regimen of Mifeprex
- At the first day, take 3 tablets of Mifeprex (600 mg) at the same time.
- At the Day 3, if you are still pregnant, take 2 misoprostol tablets (400 mcg) at the same time.
- About Day 14, this is a very important follow-up visit to be sure you are well and that you are not pregnant. Certain tests will be done to check whether your pregnancy has completely ended.
If you think there is an overdose (when you take more than the suggested quantity of something, normally a drug), here are the general symptoms of such an overdose:
Symptom: This drug causes heavy vaginal bleeding and cramping if taken in excess.
Management: If overdose is doubted, contact a poison control centre or seek a medical help immediately.
Since Mifeprex is used as a single dose, it does not have a daily dosing timetable. Call your physician for instructions if you forget any follow-up appointment. Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra dosage of this drug to make up the missed dose.
Possible Side Effects
Cramping and bleeding are predictable with this treatment. Other common symptoms of treatment include headache, nausea, vomiting, drowsiness, and diarrhoea, and dizziness, tiredness, pain in the pelvic area and back pain. These undesirable effects reduce after Day 3 and are usually vanishes by Day 14.
Severe side effects of this drug include severe vaginal bleeding, lack of sleep, stomach upset, anxiety, severe headache, fever and anaemia.
Precautions While Taking Mifeprex
Some safety measures should be monitored before taking Mifeprex or Mifepristone tablets:
- Limit the intake of alcohol use while taking Mifeprex.
- These tablets are not intended for those women who are having pregnancy more than 63 days or 9 weeks.
- Do not take this drug during breastfeeding.
- If you are uncertain about your pregnancy, avoid taking Mifeprex tablets.